Epidemiology of anal canal cancer

There are over 80 different HPV subtypes, at least 23 of which have been shown to infect the anogenital mucosa. J Natl Cancer Inst Monogr ; Epidermoid anal cancer in HIV infected patients. To continue reading this article, you must log in with your personal, hospital, or group practice subscription. As mentioned above, the UKCCCR trial failed to demonstrate a higher incidence of late effects with the use of combined chemoradiation compared with radiation alone. HPV in genital cancers at the exception of cervical cancer and anal cancers.

The three major prognostic factors are site anal canal vs. Alternately, patients may be treated with additional salvage chemoradiation therapy in the form of 5-FU, cisplatin, and a radiation boost to potentially avoid permanent colostomy. Response was assessed every 8 weeks for the first 6 months and every 12 weeks thereafter per Response Evaluation Criteria In Solid Tumors, version 1.